The invasion of the North American continent and its peoples began with the Spanish in 1565 at St. Augustine, Florida, then British in 1587 when the Plymouth Company established a settlement that they dubbed Roanoke in present-day Virginia. This first settlement failed mysteriously and in 1606, the London Company established a presence in what would become Jamestown, Virginia. From there, the French founded Quebec in 1608, then the Dutch started a colony in 1609 in present-day New York. While Native Americans resisted European efforts to amass land and power during this period, they struggled to do so while also fighting new diseases introduced by the Europeans and the slave trade.
Learn more about the colonization of North America and the plight of Native Americans with these classroom resources.